WEBVTT

1
00:00:22.880 --> 00:00:27.900
Dr. Jordan, just what is immunology and what does it have to do with cancer research?

2
00:00:27.900 --> 00:00:32.540
Immunology is the study of the natural defense mechanisms of the body.

3
00:00:33.120 --> 00:00:39.520
And we are very much interested in trying to produce antibodies against indigenous cancer cells.

4
00:00:39.980 --> 00:00:44.540
For example, as a child you were exposed to measles.

5
00:00:45.040 --> 00:00:50.000
And with this exposure you produced antibodies to the measles virus.

6
00:00:50.000 --> 00:00:58.140
The problem with cancer is much more difficult in that the tumor arises indigenously or from your own tissues.

7
00:00:58.700 --> 00:01:05.000
We hope to make the tumor tissue antigenic so that the body will produce antibodies against it.

8
00:01:06.880 --> 00:01:11.140
What steps are necessary to go about producing a cancer vaccine?

9
00:01:11.880 --> 00:01:18.560
Well, first of all, one must understand what the differences are between a normal cell and a cancer cell.

10
00:01:18.560 --> 00:01:25.840
Once this difference is detected or noted, then it can be used to actually produce the vaccine.

11
00:01:26.320 --> 00:01:33.000
That is, one must first be able to find an antigen or a substance in the tumor cell that is different

12
00:01:33.000 --> 00:01:37.140
and then utilize this difference by incorporating it into a vaccine.

13
00:01:43.420 --> 00:01:48.560
Dr. Jordan, I understand you've worked with mice experimentally for seven years.

14
00:01:48.900 --> 00:01:51.080
What results have you gotten in cancer research?

15
00:01:51.440 --> 00:01:58.220
Well, recently we have been able to actually immunize mice against their spontaneous tumors.

16
00:01:58.840 --> 00:02:07.120
And we have been employing a vaccine that we've prepared to actually protect about 30 to 40 percent of the body.

17
00:02:07.120 --> 00:02:10.060
We have also been able to immunize about 40 percent of the mice from their spontaneous tumors.

18
00:02:10.720 --> 00:02:16.200
This is very encouraging, but I should like to emphasize that these experiments are done in animals

19
00:02:16.200 --> 00:02:19.760
and that we have not yet carried these experiments to the humans.

20
00:02:59.220 --> 00:02:59.280
Thank you.

21
00:03:35.000 --> 00:03:36.960
Thank you.

22
00:03:45.480 --> 00:03:46.880
Thank you.